WebJul 15, 1986 · Accordingly, we examined other essential activation models in which the product-forming species consists of a complex of enzyme, activator, and substrate at a molar ratio of 1:1:1; none could account for the apparent tight binding of enzyme and activator. ... We therefore postulate an ordered addition, essential activation model in … WebIn order for the channels to open (e.g. at the neuromuscular junction), another signal has to bind to the receptor. ... For instance, following this activation (change in shape), the receptor may bind to proteins like G-protein which is typically located on the inner surface of the membrane. As a result, the protein is activated to attach to ...
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