Klf2 colon

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August undefined, 2024

WebFeb 5, 2024 · KLF2 is a member of the Kruppel-like transcription factor family of proteins containing highly conserved DNA-binding zinc finger domains. KLF2 participates in the differentiation and regulation of the functional activity of monocytes, T lymphocytes, adipocytes, and vascular endothelial cells. The activity of KLF2 is controlled by several … WebJul 13, 2024 · Krüppel-like factor 2 (KLF2) is a potent regulator of lymphocyte differentiation, activation and migration. However, its functional role in adaptive and humoral immunity remains elusive. ... the blood and the lamina propria of the colon and the small intestine, concomitant with their accumulation and retention in mesenteric lymph nodes and ...

KLF2 Antibody - middle region (ARP32760_P050) Aviva Systems …

http://yuxiqbs.cqvip.com/Qikan/Article/Detail?id=28278821 WebNov 25, 2010 · KLF2 (lung Krüppel-like factor) is expressed in lung, endothelial cells, and lymphocytes. 19–24 KLF2 deficiency is embryonic lethal because of severe hemorrhage resulting from defects in blood vessel integrity. 19 In T-cell biology, KLF2 has been demonstrated to regulate T-cell properties of quiescence, survival, activation, and … mays collision stamps ar

KLF2 Is a Novel Transcriptional Regulator of Endothelial ...

WebSep 24, 2013 · KLF2, KLF3, KLF4, KLF11, KLF13, KLF14, KLF15 and KLF16 all inhibit cell growth and transformation mediated by oncogenic KRAS 85. However, in mouse embryonic fibroblasts lacking p21, KLF4 bypasses... WebKLF2 belongs to the krueppel C2H2-type zinc-finger protein family. It contains 3 C2H2-type zinc fingers. KLF2 binds to the CACCC box in the beta-globin gene promoter and activates … WebAug 22, 2014 · KLF2-/ - colon ies are also smaller than wild-t ype, altho ugh. simil ar in size to KLF1-/-. It was of inter est to disti nguis h. whethe r there are few er than norm al progen itors in KLF1- mays collision center stamps ar

KLF2 Polyclonal Antibody (PA5-40591) - thermofisher.com

KLF2 is a clinical diagnostic and treatment biomarker of breast …

WebApr 16, 2024 · The results showed that KLF2 might be a tumor suppressor gene in colon cancer, which was in accordance with our experimental data. We also found that CDKN1A expression in mutant p53 colon cancer tissue was significant decreased when compared with p53 wild type colon cancer tissue, while Wnt ligand Wnt5a exhibited the highest level … WebApr 25, 2006 · The mechanisms regulating activation of monocytes remain incompletely understood. Herein we provide evidence that Kruppel-like factor 2 (KLF2) inhibits … mays collision stampsWebMar 21, 2024 · KLF2 (KLF Transcription Factor 2) is a Protein Coding gene. Diseases associated with KLF2 include Cerebral Cavernous Malformations and Spleen Cancer . Among its related pathways are White fat cell differentiation and Embryonic and Induced Pluripotent Stem Cells and Lineage-specific Markers . mays community academy

"WebApr 8, 2024 · In colon cells, CDX2 upregulated KLF4 by binding to KLF4 promoter and reducing the association of histone 3 lysine 4 trimethylation with KDM5B demethylase, and acting as a tumor suppressor. " - Klf2 colon

Klf2 colon

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WebApr 7, 2016 · The functions of interleukin-17A (IL-17A) in adipose tissues and adipocytes have not been well understood. In the present study, male mice were fed with a regular diet (n = 6, lean mice) or a high-fat diet (n = 6, obese mice) for 30 weeks. Subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) were analyzed for IL-17A levels. SAT and … WebNov 18, 2024 · KLF2 regulates metaflammation transcription in macrophages RNA-sequencing of bone marrow-derived macrophages (BMDMs) isolated from myeloid-specific KLF2 knockout (K2KO) and control (LysM) mice...

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Web维普期中文期刊服务平台，由维普资讯有限公司出品，通过对国内出版发行的14000余种科技期刊、5600万篇期刊全文进行内容分析和引文分析，为专业用户提供一站式文献服务：全文保障，文献引证关系，文献计量分析；并以期刊产品为主线、其它衍生产品或服务做补充，方便专业用户、机构用户在 ... WebMar 21, 2024 · KLF2 (KLF Transcription Factor 2) is a Protein Coding gene. Diseases associated with KLF2 include Cerebral Cavernous Malformations and Spleen Cancer . …

WebMar 9, 2024 · However, reactive oxygen species (ROS) degradation of BH4 leads to eNOS inactivation causing EC dysfunction. miR-484 and miR-93 in ECs are able to target the seed sequence of the 3’UTR of eNOS and Krüppel-like factor 2 (KLF2) mRNAs and repress protein transcription (31, 55). The sustained low expression of miR-484 in ECs under … WebMay 10, 2004 · Endo-KLF2 refers to endogenous human KLF2. (B) KLF2 inhibits IL-1β–mediated induction of VCAM-1 and E-selectin protein levels. Experiments were performed as described in A except cells were harvested for total protein and Western blot analysis was performed. (C) KLF2 inhibits VCAM-1 and E-selectin in response to multiple …

WebMay 30, 2013 · Kruppel-like factors (KLFs) is a subclass of the zinc-finger family of transcription factors important in cell differentiation and growth. 6 KLF2 is highly expressed in vascular endothelium and orchestrates endothelium-dependent vascular homeostasis in health. 7, 8 KLF2 expression in the endothelium is upregulated by laminar shear stress … WebMay 29, 2014 · Maturation as well as antigen-dependent activation of B cells is accompanied by alternating phases of proliferation and quiescence. We and others have …

WebApr 13, 2024 · KLF2 expression levels were found to be reduced in advanced cancer stages and grades, while positively correlated with the expression of estrogen receptor (ER), progesterone receptor (PR), and tumor size in breast cancer, according to the Tumor Immune Estimation Resource and Human Protein Atlas databases. Background: As a …

mays collyhurstWebMar 3, 2024 · MAP3K2 is a serine/threonine kinase belonging to the MAP3K superfamily 11. To investigate the role of MAP3K2 in the intestine, we added dextran sodium sulfate (DSS), which causes colitis, to the... mays community academy indianaWebKLF2, also known as lung Kruppel-like factor, is a 355 amino acid protein that is predominantly expressed in the lung, spleen, and heart tissue [19] ( Table 1 ). KLF4 also known as gut-enriched Kruppel-like factor or epithelial zinc finger, is a 470 amino acid protein that is centrally distributed in epithelial cells of the gastrointestinal tract. mays computersWebTarget Name: KLF2 Sample Tissue: Human MCF7 Whole Cell Antibody Dilution: 1ug/ml Immunohistochemistry with Human lung Immunohistochemistry with Human Colon, myenteric plexus Immunohistochemistry with Human … mays conservatoryWebMar 19, 2024 · In colon cancer and rectal cancer, KLFs were also shown to be associated with a variety of immune cells. ... in CRC patients, we used various online analytic tools, including ONCOMINE, TCGA, cBioPortal, and the TIMER database. KLF2-6, KLF8-10, KLF12-15, and KLF17 mRNA expression levels were dramatically downregulated in CRC tissues, … may scofieldWebKLF2 Antibody (PA5-115479) in IHC (P) Immunohistochemistry analysis of KLF2 in human colorectal cancer and adjacent normal tissues. Samples were treated with formaldehyde … mays computer and outdoors raidedWebApr 1, 2024 · Introduction. Krüppel-like factor 2 (KLF2), a zinc-finger transcription factor, is a crucial regulator of differentiation, proliferation and activation of various cell types, including T- and B-lymphocytes 1, 2, 3.Within the B cell lineage, KLF2 expression is induced during early B cell development in the bone marrow (BM) by signals of the pre-B cell receptor and … mays coppice farm