Kif14 structure
WebPredicted to be part of Kinesin complex. Predicted to be active in microtubule. Predicted to colocalize with plasma membrane. Human ortholog(s) of this gene implicated in Meckel … WebFeedback on structure: Contact DeepMind If you want to share your feedback on an AlphaFold structure prediction, ... Kinesin-like protein KIF14. Gene. KIF14. Source …
Kif14 structure
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WebKIF14. The N- terminal of the coiled- coil domain of Citron-K directly interacts with the 2nd coiled-coil domain of KIF14. The localization of KIF14 and citron kinase to the central … Web15 jun. 2024 · The KIF14 motor domain of the MT-K748-ADP structure is colored by the distance to equivalent Cα atoms in the microtubule-unbound structure (semitransparent …
Web26 feb. 2024 · KIF14 is a mitotic kinesin whose malfunction is associated with cerebral and renal developmental defects and several cancers. Like other kinesins, KIF14 couples ATP hydrolysis and microtubule binding to the generation of mechanical work, but the coupling mechanism between these processes is still not fully clear ... Macromolecules WebStructural basis of mechano-chemical coupling by the mitotic kinesin KIF14 by: Matthieu P.M.H. Benoit, et al. Published: (2024-06-01) Observations on spontaneous tumor formation in mice overexpressing mitotic kinesin Kif14 by: Kamakshi Sishtla, et …
Web2004006008001000120014001600Kinesin motorFHAATPPolar residuesPolar residuesRequired for PRC1-bindingDisorderedRequired for microtubule-binding with high ... WebMicrotubule motor protein that binds to microtubules with high affinity through each tubulin heterodimer and has an ATPase activity (By similarity). Plays a role in many processes like cell division, cytokinesis and also in cell proliferation and apoptosis (PubMed:24784001, PubMed:16648480). During cytokinesis, targets to central spindle and midbody through …
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Web26 aug. 2014 · Structure of kif14: an engaging molecular motor. Structure of kif14: an engaging molecular motor. Structure of kif14: an engaging molecular motor J Mol Biol. … fz400r12ke4hosa1WebAbout KIF14 Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:200,551,497-200,620,751 (from NCBI) This gene has 2 transcripts (splice variants), 199 orthologues, … fz400r12kp4WebSyntax; Advanced Search; New. All new items; Books; Journal articles; Manuscripts; Topics. All Categories; Metaphysics and Epistemology att sunvalley mallWeb15 jun. 2024 · Cryo-electron microscopy (cryo-EM) structures of KIF14 motor domain complexes. To elucidate conformational changes related to the microtubule-bound KIF14 motor domain ATPase cycle, and their possible modulation by the neck-linker or a partner motor domain, we determined the cryo-EM structures of microtubule (MT) complexes of … att summit pointWebAssigned HPA protein class (es) for the encoded protein (s). Number of protein-coding transcripts from the gene as defined by Ensembl. A summary of the overall protein … att summitWeb15 jun. 2024 · KIF14 is a mitotic kinesin whose malfunction is associated with cerebral and renal developmental defects and several cancers. Like other kinesins, KIF14 … fz40423491WebIntroduction The Tousled-like kinases 1 and 2 (TLK1 and TLK2) are involved in many fundamental processes, including DNA replication, cell cycle checkpoint recovery and chromatin remodelling. Mutations in TLK2 were recently associated with ‘Mental Retardation Autosomal Dominant 57’ (MRD57, MIM# 618050), a neurodevelopmental disorder … att sullivan mo