Circpvt1 review
WebAug 11, 2024 · Results. circPVT1 and TRIAP1 were highly expressed, and miR-137 was decreased in DXR-resistant osteosarcoma tissues and cells. Moreover, circPVT1 knockdown could boost DXR sensitivity by inhibiting DXR-caused proliferation and DXR-induced apoptosis in DXR-resistant osteosarcoma cells in vitro.
Circpvt1 review
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WebJan 28, 2024 · Here, we review circPVT1 origin and biogenesis highlighting the most important mechanisms through which it plays a fundamental role in oncogenesis, such … WebOverexpressed circPVT1, a potential new circular RNA biomarker, contributes to doxorubicin and cisplatin resistance of osteosarcoma cells by regulating ABCB1 ... Geller DS, Gorlick R. Osteosarcoma: a review of diagnosis, management, and treatment strategies. Clinical advances in hematology & oncology: H&O. 2010;8:705-18 23. Zhou …
WebCircPVT1 as potential clinical biomarker. Although studies on circPVT1 in malignancy remained scanty, significant association of the candidate with disease onset and outcome indicated it as a promising biomarker of … WebCircPVT1 has been found to increase proliferation of gastric cancer cell through serving as a molecular sponge for miR-125 family members . Moreover, expression of circPVT1 …
WebApr 3, 2024 · CircPVT1 acts as a competing endogenous RNA (ceRNA) to sponge miR-181a-2-3p, promoting the expression of ESR1 and downstream ERα-target genes and … WebMay 11, 2024 · This review introduces the biogenesis of circRNAs and summarizes the roles played by circRNAs in human diseases. ... circ-TTBK2 (ref. 38), and circPVT1 (ref. 39) are examples of circRNAs that act ...
WebDec 20, 2024 · Using samples from 115 HNSCC patients, we find that circPVT1 is over-expressed in tumors compared to matched non-tumoral tissues, with particular enrichment in patients with TP53 mutations. circPVT1 up- and down-regulation determine, respectively, an increase and a reduction of the malignant phenotype in HNSCC cell lines.
WebDec 20, 2024 · In order to determine whether the up-regulation of circPVT1 correlated with the TP53 mutations, we compared the circPVT1 expression of mut-p53 and wild-type … phillip beach south carolinaWebAug 8, 2024 · This Review describes recent progress in our understanding of the biogenesis and biology of circRNAs and delineates modern technologies that will further advance … phillip beard attorneyWebApr 1, 2024 · circPVT1 and lncPVT1 shared features and functions in human cancer cells. Pathways regulated by both circPVT1 and lncPVT1 in cancer, as documented in the … trymer fellowes electron a4 ceneoWebJun 10, 2024 · CircPVT1 promotes LUSC progression via HuR/circPVT1/miR-30d and miR-30e/CCNF cascade. Also, it acts as a novel diagnostic biomarker or treatment target of individuals diagnosed with LUSC. Background Lung cancer (LC) accounts for the highest rate of cancer incidence and mortalities across the globe. phillip beardmoreWebNov 4, 2024 · CircPVT1 (hsa_circ_0001821) is a cancer-related circular RNA (circRNA) that originated from a genomic locus on chromosome 8q24. This locus has been … phillip beard attorney xeniaWebNov 2, 2024 · The Verdict: A Multi-Use Winner. While the REI Co-op DRT 1.2 is a slightly smoother, slightly larger and more trail-capable bike, it’s impossible to ignore the … trymer fox honeyWebMay 27, 2024 · Oral squamous cell carcinoma (OSCC) is a common malignant tumor occurring in the oral cavity. Circular RNAs (circRNAs) play a crucial regulatory role in many cancers. This study aimed to investigate the function of circRNA plasmacytoma variant translocation 1 (PVT1) (circPVT1) in OSCC and its potential mechanism. The levels of … phillip bearden